Little's Pharmacy brings together pharmacist expertise, friendly hometown service, and a deep commitment to the rural Mississippi communities we have served for generations.
At Little's Pharmacy, we've been serving Smith County since 1947, a family-founded pharmacy whose legacy of trust and personalized care has been passed down through generations.
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Years Serving Raleigh
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Delivery Around Raleigh
For over eight decades, Little's Pharmacy has served Raleigh and the surrounding rural communities with a balance of trusted independent pharmacy care and modern technology through the Good Neighbor Pharmacy network. We are known for free local delivery, walk-in immunizations, medication synchronization, and full Medicare Part D support. As the only pharmacy located in Raleigh, we proudly carry forward the multi-generational Little family legacy at 122 Main Street.
Everything we do is centered on helping our neighbors feel informed, supported, and cared for through personal pharmacist attention, full-service offerings, and deep community roots in Smith County.
The people filling your prescriptions and answering the phone at Little’s. Open any card to read their story in their own words.
Transfer your prescription online or call (601) 782-4552 to get started with Little's Pharmacy in Raleigh.
