Little's Pharmacy brings together pharmacist expertise, friendly hometown service, and a deep commitment to the rural Mississippi communities we have served for generations.
At Little's Pharmacy, we've been serving Smith County since 1947, a family-founded pharmacy whose legacy of trust and personalized care has been passed down through generations.
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Years Serving Raleigh
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Delivery Around Raleigh
For over eight decades, Little's Pharmacy has served Raleigh and the surrounding rural communities with a balance of trusted independent pharmacy care and modern technology through the Good Neighbor Pharmacy network. We are known for free local delivery, walk-in immunizations, medication synchronization, and full Medicare Part D support. As the only pharmacy located in Raleigh, we proudly carry forward the multi-generational Little family legacy at 122 Main Street.
Everything we do is centered on helping our neighbors feel informed, supported, and cared for through personal pharmacist attention, full-service offerings, and deep community roots in Smith County.
Little's Pharmacy is the only pharmacy in Raleigh, MS, locally owned and operated for more than 79 years with a clean BBB A+ record and a multi-generational Little family legacy.
We offer free prescription delivery within 10 miles of Raleigh, plus curbside pickup right at our Main Street pharmacy.
Beyond prescriptions, we carry quality diabetic supplies and durable medical equipment, so you can find the everyday health essentials you need close to home without driving to a big-box store.
We offer medication synchronization, multi-dose compliance packaging, Medication Therapy Management, prior authorization help, and Medicare Part D plan reviews to make every refill easier.
The people filling your prescriptions and answering the phone at Little’s. Open any card to read their story in their own words.
Transfer your prescription online or call (601) 782-4552 to get started with Little's Pharmacy in Raleigh.
